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抑制剂 & 化合物

40

重组蛋白

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Cat. No. Product Name Target Signaling Pathways
T82436 Etigilimab

OMP-313M32

Etigilimab (OMP-313M32) 为人源化IgG1单克隆抗体,旨在阻断TIGIT与PVR (CD155;脊髓灰质炎病毒受体)间的结合,进而抑制信号传导,通过诱导靶细胞凋亡实现其作用。

化合物

Etigilimab
Cat.No: T82436
Synonym: OMP-313M32
Target:
Cat. No. Product Name Species Expression System
TMPY-01612 CD155/PVR Protein, Rhesus, Recombinant (His)

poliovirus receptor

Rhesus HEK293 Cells
CD155/PVR Protein, Rhesus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 35.8 kDa and the accession number is Q0MSE6.
TMPJ-00651 CD155/PVR Protein, Human, Recombinant (aa 21-343, His)

Poliovirus Receptor,PVS,Nectin-Like Protei...

Human HEK293 Cells
Poliovirus Receptor (PVR) is a 70 kDa type I transmembrane single-span glycoprotein that belongs to the nectin-like (Necl) family and was originally identified based on its ability to mediate the cell attachment and entry of poliovirus (PV), an etiologic agent of the central nervous system disease poliomyelitis. PVR contains three Ig-like extracellular domains, a transmembrane segment, and a cytoplasmic tail. The normal cellular function of PVR maybe the involvement of intercellular adhension be...
TMPY-05791 CD155/PVR Protein, Mouse, Recombinant (mFc)

Taa1,3830421F03Rik,poliovirus receptor,nec...

Mouse HEK293 Cells
CD155/PVR Protein, Mouse, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 60.78 kDa and the accession number is Q8K094.
TMPY-00699 CD155/PVR Protein, Human, Recombinant (hFc)

poliovirus receptor,NECL5,HVED,PVS,Necl-5,...

Human HEK293 Cells
CD155/PVR Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 61.8 kDa and the accession number is P15151-1.
TMPY-01386 CD155/PVR Protein, Human, Recombinant (His)

NECL5,TAGE4,PVS,CD155,HVED,Necl-5,poliovirus re...

Human HEK293 Cells
CD155/PVR Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 36.5 kDa and the accession number is P15151-1.
TMPY-00747 Nectin-2 Protein, Human, Recombinant (His)

PVRR2,Nectin-2,poliovirus receptor-related...

Human HEK293 Cells
Nectin-2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 36.2 kDa and the accession number is Q92692-2.
TMPY-00748 Nectin-2 Protein, Human, Recombinant

PRR2,Nectin-2,PVRR2,poliovirus receptor-re...

Human HEK293 Cells
Nectin-2 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 36.2 kDa and the accession number is Q92692-2.
TMPY-01610 CD155/PVR Protein, Rat, Recombinant (His)

poliovirus receptor

Rat HEK293 Cells
CD155/PVR Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 35.8 kDa and the accession number is A6J8V8.
TMPY-05579 PVRL1/NECTIN1 Protein, Human, Recombinant (hFc), Biotinylated

PRR1,ED4,PVRR,nectin-1,OFC7,SK-12,CD111,CLPED1,HVEC,poli...

Human HEK293 Cells
PVRL1/NECTIN1 Protein, Human, Recombinant (hFc), Biotinylated is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 61 kDa and the accession number is Q15223-1.
TMPY-03030 PVRL1/NECTIN1 Protein, Rat, Recombinant (hFc)

poliovirus receptor-related 1 (herpesvirus...

Rat HEK293 Cells
PVRL1/NECTIN1 Protein, Rat, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 63.3 kDa and the accession number is A6J3U6.
TMPY-03036 Nectin-2 Protein, Rat, Recombinant (His)

poliovirus receptor-related 2 (herpesvirus...

Rat HEK293 Cells
Nectin-2 Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 36 kDa and the accession number is Q9ESS6.
TMPY-02937 PVRL1/NECTIN1 Protein, Rat, Recombinant (His)

poliovirus receptor-related 1 (herpesvirus...

Rat HEK293 Cells
PVRL1/NECTIN1 Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 37.6 kDa and the accession number is A6J3U6.
TMPY-02561 Nectin-2 Protein, Cynomolgus, Recombinant (His)

poliovirus receptor-related 2 (herpesvirus...

Cynomolgus HEK293 Cells
Nectin-2 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 37.2 kDa and the accession number is Q0MSE5.
TMPY-05596 CD155/PVR Protein, Human, Recombinant (His & Avi), Biotinylated

NECL5,Necl-5,TAGE4,HVED,CD155,PVS,poliovirus re...

Human HEK293 Cells
CD155/PVR Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 38.3 kDa and the accession number is P15151.2.
TMPY-06133 CD155/PVR Protein, Human, Recombinant (hFc & Avi), Biotinylated

TAGE4,CD155,NECL5,poliovirus receptor,HVED...

Human HEK293 Cells
CD155/PVR Protein, Human, Recombinant (hFc & Avi), Biotinylated is expressed in HEK293 mammalian cells with hFc and Avi tag. The predicted molecular weight is 63.6 kDa and the accession number is P15151-1.
TMPJ-01231 Nectin-4 Protein, Mouse, Recombinant (aa 31-349, hFc)

Ig superfamily receptor LNIR,PRR4,Nectin-4,PVRL4,LN...

Mouse HEK293 Cells
Nectin-4 Protein, Mouse, Recombinant (aa 31-349, hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 75-85 KDa and the accession number is Q8R007.
TMPY-00762 CD155/PVR Protein, Mouse, Recombinant (His)

poliovirus receptor,D7Ertd458e,mE4,Taa1,ne...

Mouse HEK293 Cells
CD155/PVR Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 28 kDa and the accession number is Q8K094.
TMPY-05597 CD155/PVR Protein, Mouse, Recombinant (hFc & Avi), Biotinylated

PVS,Taa1,Tage4,CD155,poliovirus receptor,m...

Mouse HEK293 Cells
CD155/PVR Protein, Mouse, Recombinant (hFc & Avi), Biotinylated is expressed in HEK293 mammalian cells with hFc and Avi tag. The predicted molecular weight is 62.9 kDa and the accession number is Q8K094.
TMPJ-01232 Nectin-4 Protein, Mouse, Recombinant (aa 31-349, His)

PRR4,Nectin-4,Poliovirus receptor-related ...

Mouse HEK293 Cells
Nectin-4 Protein, Mouse, Recombinant (aa 31-349, His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 40-50 KDa and the accession number is Q8R007.
TMPJ-00312 Nectin-4 Protein, Human, Recombinant (mFc)

PVRL4,LNIR,Nectin-4,Ig superfamily receptor LNIR,

Human HEK293 Cells
Nectin-4 Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with C-mFc tag. The predicted molecular weight is 80-90 KDa and the accession number is Q96NY8.
TMPJ-00308 Nectin-4 Protein, Cynomolgus, Recombinant (aa 32-349, hFc)

PRR4,Ig superfamily receptor LNIR,PVRL4,Poliovi...

Cynomolgus HEK293 Cells
Nectin-4 Protein, Cynomolgus, Recombinant (aa 32-349, hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 80-90 KDa and the accession number is L0N6D9.
TMPJ-00311 Nectin-4 Protein, Human, Recombinant (aa 32-351, hFc)

PRR4,PVRL4,LNIR,Nectin-4,Ig superfamily receptor LN...

Human HEK293 Cells
Nectin-4 Protein, Human, Recombinant (aa 32-351, hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 75-90 KDa and the accession number is Q96NY8.
TMPJ-00309 Nectin-4 Protein, Cynomolgus, Recombinant (aa 32-349, His)

LNIR,Ig superfamily receptor LNIR,PRR4,Poliovir...

Cynomolgus HEK293 Cells
Nectin-4 Protein, Cynomolgus, Recombinant (aa 32-349, His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 38-50 KDa and the accession number is L0N6D9.
TMPJ-00310 Nectin-4 Protein, Human, Recombinant (His & Avi), Biotinylated

Nectin-4,PVRL4,LNIR,PRR4,Ig superfamily receptor LN...

Human HEK293 Cells
Nectin-4 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-6xHis-Avi tag. The predicted molecular weight is 40-50 KDa and the accession number is Q96NY8.
TMPY-00746 Nectin-2 Protein, Human, Recombinant (hFc)

Nectin-2,HVEB,poliovirus receptor-related ...

Human HEK293 Cells
Nectin-2 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 62.3 kDa and the accession number is Q92692-2.
TMPY-06383 Nectin-2 Protein, Human, Recombinant (His & Avi), Biotinylated

poliovirus receptor-related 2 (herpesvirus...

Human HEK293 Cells
Nectin-2 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 38.80 kDa and the accession number is Q92692-2.
TMPY-06295 Nectin-2 Protein, Human, Recombinant (hFc & Avi), Biotinylated

Nectin-2,HVEB,PVRR2,CD112,PRR2,poliovirus recep...

Human HEK293 Cells
Nectin-2 Protein, Human, Recombinant (hFc & Avi), Biotinylated is expressed in HEK293 mammalian cells with hFc and Avi tag. The predicted molecular weight is 64.08 kDa and the accession number is Q92692-2.
TMPY-01150 Nectin-2 Protein, Mouse, Recombinant (His)

MPH,Pvs,Pvr,Cd112,AI325026,AI987993,poliovirus ...

Mouse HEK293 Cells
Nectin-2 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 36 kDa and the accession number is P32507-1.
TMPY-05495 Nectin-3 Protein, Human, Recombinant (hFc)

CDw113,FLJ90624,PVRL3,DKFZp566B0846,nectin-3,PRR3,CD113,PPR3...

Human HEK293 Cells
Nectin-3 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 64.4 kDa and the accession number is Q9NQS3-1.
TMPJ-00323 Nectin-2 Protein, Mouse, Recombinant (hFc)

Herpes Virus Entry Mediator B,PVRL2,Poliovirus ...

Mouse HEK293 Cells
CD112 is a type I transmembrane glycoprotein belonging to the Immunoglobulin superfamily. It comprises one Ig-like V-type domain and two Ig-like C2-type domains in the extracellular region. The V domain is believed to mediate nectin binding to its ligands. Nectin2 is known to bind the pseudorabies virus, and herpes simplex virus2 (HSV2), involving in cell to cell spreading of these viruses. It does not bind poliovirus. As a homophilic adhesion molecule, CD112 is found concentrated in adherens ju...
TMPY-05196 PVRL1/NECTIN1 Protein, Mouse, Recombinant (hFc)

AI835281,poliovirus receptor-related 1 (he...

Mouse HEK293 Cells
PVRL1/NECTIN1 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 62.9 kDa and the accession number is Q9JKF6.
TMPY-05560 PVRL1/NECTIN1 Protein, Mouse, Recombinant (His)

PRR1,PRR,nectin-1,HIgR,Cd111,AI835281,HveC,poliovirus

Mouse HEK293 Cells
PVRL1/NECTIN1 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 37.6 kDa and the accession number is Q9JKF6.
TMPY-01154 Nectin-3 Protein, Human, Recombinant (His)

PRR3,FLJ90624,PVRL3,poliovirus receptor-re...

Human HEK293 Cells
Nectin-3 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 39.3 kDa and the accession number is Q9NQS3-1.
TMPY-01571 PVRL1/NECTIN1 Protein, Human, Recombinant (hFc)

HV1S,ED4,poliovirus receptor-related 1 (he...

Human HEK293 Cells
PVRL1/NECTIN1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 61 kDa and the accession number is Q15223-1.
TMPY-01572 PVRL1/NECTIN1 Protein, Human, Recombinant (His)

HVEC,ED4,PRR1,PVRR1,nectin-1,HIgR,poliovirus re...

Human HEK293 Cells
PVRL1/NECTIN1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 35.4 kDa and the accession number is Q15223-1.
TMPK-00319 Nectin-3 Protein, Human, Recombinant (His & Avi), Biotinylated

PVRL3,CDw113,PPR3,CD113,FLJ90624,PVRR3,PRR3

Human HEK293 Cells
The Nectin family has at least four members (Nectin-1‑4), all of which show alternate splicing, a transmembrane (TM) region (except for Nectin-1 gamma), and three extracellular Ig-domains. Nectins are highly homologous to the human receptor for poliovirus, and as such, have been alternatively-named poliovirus receptor-related proteins. They do not, however, appear to bind poliovirus. Nectin-3 (also named PRR3, CD113, and PVRL3) is an 83 kDa, type I TM glycoprotein.
TMPK-00318 Nectin-3 Protein, Human, Recombinant (His & Avi)

PVRR3,PRR3,CDw113,FLJ90624,PVRL3,PPR3,CD113

Human HEK293 Cells
The Nectin family has at least four members (Nectin-1‑4), all of which show alternate splicing, a transmembrane (TM) region (except for Nectin-1 gamma), and three extracellular Ig-domains. Nectins are highly homologous to the human receptor for poliovirus, and as such, have been alternatively-named poliovirus receptor-related proteins. They do not, however, appear to bind poliovirus. Nectin-3 (also named PRR3, CD113, and PVRL3) is an 83 kDa, type I TM glycoprotein. Its precursor is 549 amino aci...
TMPK-00471 PVRIG Protein, Mouse, Recombinant (hFc & Avi), Biotinylated

MGC2463,MGC104322,LPD,C7orf15,ALS2CR18,PREL2,ALS2CR9,RMO1,PR...

Mouse HEK293 Cells
Murine PVRIG interacted weakly with poliovirus receptor (PVR) but bound poliovirus receptor-like 2 (PVRL2) strongly, making the latter its principal ligand.PVRIG is an inducible checkpoint receptor and that targeting PVRIG-PVRL2 interactions results in increased CD8+ T-cell function and reduced tumor growth. PVRIG Protein, Mouse, Recombinant (hFc & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-hFc-Avi tag. The predicted molecular weight is 42.7 kDa and the accession number is ...
TMPK-00470 PVRIG Protein, Mouse, Recombinant (hFc & Avi)

PREL-2,RMO1,MGC2463,C7orf15,MGC104322,PREL2,PVRIG,LPD,MGC138...

Mouse HEK293 Cells
Murine PVRIG interacted weakly with poliovirus receptor (PVR) but bound poliovirus receptor-like 2 (PVRL2) strongly, making the latter its principal ligand.PVRIG is an inducible checkpoint receptor and that targeting PVRIG-PVRL2 interactions results in increased CD8+ T-cell function and reduced tumor growth. PVRIG Protein, Mouse, Recombinant (hFc & Avi) is expressed in HEK293 mammalian cells with C-hFc-Avi tag. The predicted molecular weight is 42.70 kDa and the accession number is A0A1B0GS01.
TMPK-00260 CD155/PVR Protein, Human, Recombinant (His & Avi)

NECL5,PVSFLJ25946,Necl-5,CD155,Tage4,PVR,HVED,FLJ25946,necti...

Human HEK293 Cells
CD155 is a cell surface adhesion molecule functioning in tumor cell migration, invasion, and metastasis, and not surprisingly, is also designated as a common tumor-associated antigen. CD155 is also recognized by NK cells to induce their cytotoxicity. CD155 is also commonly referred to as the "poliovirus receptor," or PVR.

重组蛋白

CD155/PVR Protein, Rhesus, Recombinant (His)
Cat.No: TMPY-01612
Species: Rhesus
Expression System: HEK293 Cells
CD155/PVR Protein, Human, Recombinant (aa 21-343, His)
Cat.No: TMPJ-00651
Species: Human
Expression System: HEK293 Cells
CD155/PVR Protein, Mouse, Recombinant (mFc)
Cat.No: TMPY-05791
Species: Mouse
Expression System: HEK293 Cells
CD155/PVR Protein, Human, Recombinant (hFc)
Cat.No: TMPY-00699
Species: Human
Expression System: HEK293 Cells
CD155/PVR Protein, Human, Recombinant (His)
Cat.No: TMPY-01386
Species: Human
Expression System: HEK293 Cells
Nectin-2 Protein, Human, Recombinant (His)
Cat.No: TMPY-00747
Species: Human
Expression System: HEK293 Cells
Nectin-2 Protein, Human, Recombinant
Cat.No: TMPY-00748
Species: Human
Expression System: HEK293 Cells
CD155/PVR Protein, Rat, Recombinant (His)
Cat.No: TMPY-01610
Species: Rat
Expression System: HEK293 Cells
PVRL1/NECTIN1 Protein, Human, Recombinant (hFc), Biotinylated
Cat.No: TMPY-05579
Species: Human
Expression System: HEK293 Cells
PVRL1/NECTIN1 Protein, Rat, Recombinant (hFc)
Cat.No: TMPY-03030
Species: Rat
Expression System: HEK293 Cells
Nectin-2 Protein, Rat, Recombinant (His)
Cat.No: TMPY-03036
Species: Rat
Expression System: HEK293 Cells
PVRL1/NECTIN1 Protein, Rat, Recombinant (His)
Cat.No: TMPY-02937
Species: Rat
Expression System: HEK293 Cells
Nectin-2 Protein, Cynomolgus, Recombinant (His)
Cat.No: TMPY-02561
Species: Cynomolgus
Expression System: HEK293 Cells
CD155/PVR Protein, Human, Recombinant (His & Avi), Biotinylated
Cat.No: TMPY-05596
Species: Human
Expression System: HEK293 Cells
CD155/PVR Protein, Human, Recombinant (hFc & Avi), Biotinylated
Cat.No: TMPY-06133
Species: Human
Expression System: HEK293 Cells
Nectin-4 Protein, Mouse, Recombinant (aa 31-349, hFc)
Cat.No: TMPJ-01231
Species: Mouse
Expression System: HEK293 Cells
CD155/PVR Protein, Mouse, Recombinant (His)
Cat.No: TMPY-00762
Species: Mouse
Expression System: HEK293 Cells
CD155/PVR Protein, Mouse, Recombinant (hFc & Avi), Biotinylated
Cat.No: TMPY-05597
Species: Mouse
Expression System: HEK293 Cells
Nectin-4 Protein, Mouse, Recombinant (aa 31-349, His)
Cat.No: TMPJ-01232
Species: Mouse
Expression System: HEK293 Cells
Nectin-4 Protein, Human, Recombinant (mFc)
Cat.No: TMPJ-00312
Species: Human
Expression System: HEK293 Cells
Nectin-4 Protein, Cynomolgus, Recombinant (aa 32-349, hFc)
Cat.No: TMPJ-00308
Species: Cynomolgus
Expression System: HEK293 Cells
Nectin-4 Protein, Human, Recombinant (aa 32-351, hFc)
Cat.No: TMPJ-00311
Species: Human
Expression System: HEK293 Cells
Nectin-4 Protein, Cynomolgus, Recombinant (aa 32-349, His)
Cat.No: TMPJ-00309
Species: Cynomolgus
Expression System: HEK293 Cells
Nectin-4 Protein, Human, Recombinant (His & Avi), Biotinylated
Cat.No: TMPJ-00310
Species: Human
Expression System: HEK293 Cells
Nectin-2 Protein, Human, Recombinant (hFc)
Cat.No: TMPY-00746
Species: Human
Expression System: HEK293 Cells
Nectin-2 Protein, Human, Recombinant (His & Avi), Biotinylated
Cat.No: TMPY-06383
Species: Human
Expression System: HEK293 Cells
Nectin-2 Protein, Human, Recombinant (hFc & Avi), Biotinylated
Cat.No: TMPY-06295
Species: Human
Expression System: HEK293 Cells
Nectin-2 Protein, Mouse, Recombinant (His)
Cat.No: TMPY-01150
Species: Mouse
Expression System: HEK293 Cells
Nectin-3 Protein, Human, Recombinant (hFc)
Cat.No: TMPY-05495
Species: Human
Expression System: HEK293 Cells
Nectin-2 Protein, Mouse, Recombinant (hFc)
Cat.No: TMPJ-00323
Species: Mouse
Expression System: HEK293 Cells
PVRL1/NECTIN1 Protein, Mouse, Recombinant (hFc)
Cat.No: TMPY-05196
Species: Mouse
Expression System: HEK293 Cells
PVRL1/NECTIN1 Protein, Mouse, Recombinant (His)
Cat.No: TMPY-05560
Species: Mouse
Expression System: HEK293 Cells
Nectin-3 Protein, Human, Recombinant (His)
Cat.No: TMPY-01154
Species: Human
Expression System: HEK293 Cells
PVRL1/NECTIN1 Protein, Human, Recombinant (hFc)
Cat.No: TMPY-01571
Species: Human
Expression System: HEK293 Cells
PVRL1/NECTIN1 Protein, Human, Recombinant (His)
Cat.No: TMPY-01572
Species: Human
Expression System: HEK293 Cells
Nectin-3 Protein, Human, Recombinant (His & Avi), Biotinylated
Cat.No: TMPK-00319
Species: Human
Expression System: HEK293 Cells
Nectin-3 Protein, Human, Recombinant (His & Avi)
Cat.No: TMPK-00318
Species: Human
Expression System: HEK293 Cells
PVRIG Protein, Mouse, Recombinant (hFc & Avi), Biotinylated
Cat.No: TMPK-00471
Species: Mouse
Expression System: HEK293 Cells
PVRIG Protein, Mouse, Recombinant (hFc & Avi)
Cat.No: TMPK-00470
Species: Mouse
Expression System: HEK293 Cells
CD155/PVR Protein, Human, Recombinant (His & Avi)
Cat.No: TMPK-00260
Species: Human
Expression System: HEK293 Cells
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