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Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T82436 |
Etigilimab
OMP-313M32 |
||
Etigilimab (OMP-313M32) 为人源化IgG1单克隆抗体,旨在阻断TIGIT与PVR (CD155;脊髓灰质炎病毒受体)间的结合,进而抑制信号传导,通过诱导靶细胞凋亡实现其作用。 |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-01612 |
CD155/PVR Protein, Rhesus, Recombinant (His)
poliovirus receptor |
Rhesus | HEK293 Cells |
CD155/PVR Protein, Rhesus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 35.8 kDa and the accession number is Q0MSE6. | |||
TMPJ-00651 |
CD155/PVR Protein, Human, Recombinant (aa 21-343, His)
Poliovirus Receptor,PVS,Nectin-Like Protei... |
Human | HEK293 Cells |
Poliovirus Receptor (PVR) is a 70 kDa type I transmembrane single-span glycoprotein that belongs to the nectin-like (Necl) family and was originally identified based on its ability to mediate the cell attachment and entry of poliovirus (PV), an etiologic agent of the central nervous system disease poliomyelitis. PVR contains three Ig-like extracellular domains, a transmembrane segment, and a cytoplasmic tail. The normal cellular function of PVR maybe the involvement of intercellular adhension be... | |||
TMPY-05791 |
CD155/PVR Protein, Mouse, Recombinant (mFc)
Taa1,3830421F03Rik,poliovirus receptor,nec... |
Mouse | HEK293 Cells |
CD155/PVR Protein, Mouse, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 60.78 kDa and the accession number is Q8K094. | |||
TMPY-00699 |
CD155/PVR Protein, Human, Recombinant (hFc)
poliovirus receptor,NECL5,HVED,PVS,Necl-5,... |
Human | HEK293 Cells |
CD155/PVR Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 61.8 kDa and the accession number is P15151-1. | |||
TMPY-01386 |
CD155/PVR Protein, Human, Recombinant (His)
NECL5,TAGE4,PVS,CD155,HVED,Necl-5,poliovirus re... |
Human | HEK293 Cells |
CD155/PVR Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 36.5 kDa and the accession number is P15151-1. | |||
TMPY-00747 |
Nectin-2 Protein, Human, Recombinant (His)
PVRR2,Nectin-2,poliovirus receptor-related... |
Human | HEK293 Cells |
Nectin-2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 36.2 kDa and the accession number is Q92692-2. | |||
TMPY-00748 |
Nectin-2 Protein, Human, Recombinant
PRR2,Nectin-2,PVRR2,poliovirus receptor-re... |
Human | HEK293 Cells |
Nectin-2 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 36.2 kDa and the accession number is Q92692-2. | |||
TMPY-01610 |
CD155/PVR Protein, Rat, Recombinant (His)
poliovirus receptor |
Rat | HEK293 Cells |
CD155/PVR Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 35.8 kDa and the accession number is A6J8V8. | |||
TMPY-05579 |
PVRL1/NECTIN1 Protein, Human, Recombinant (hFc), Biotinylated
PRR1,ED4,PVRR,nectin-1,OFC7,SK-12,CD111,CLPED1,HVEC,poli... |
Human | HEK293 Cells |
PVRL1/NECTIN1 Protein, Human, Recombinant (hFc), Biotinylated is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 61 kDa and the accession number is Q15223-1. | |||
TMPY-03030 |
PVRL1/NECTIN1 Protein, Rat, Recombinant (hFc)
poliovirus receptor-related 1 (herpesvirus... |
Rat | HEK293 Cells |
PVRL1/NECTIN1 Protein, Rat, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 63.3 kDa and the accession number is A6J3U6. | |||
TMPY-03036 |
Nectin-2 Protein, Rat, Recombinant (His)
poliovirus receptor-related 2 (herpesvirus... |
Rat | HEK293 Cells |
Nectin-2 Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 36 kDa and the accession number is Q9ESS6. | |||
TMPY-02937 |
PVRL1/NECTIN1 Protein, Rat, Recombinant (His)
poliovirus receptor-related 1 (herpesvirus... |
Rat | HEK293 Cells |
PVRL1/NECTIN1 Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 37.6 kDa and the accession number is A6J3U6. | |||
TMPY-02561 |
Nectin-2 Protein, Cynomolgus, Recombinant (His)
poliovirus receptor-related 2 (herpesvirus... |
Cynomolgus | HEK293 Cells |
Nectin-2 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 37.2 kDa and the accession number is Q0MSE5. | |||
TMPY-05596 |
CD155/PVR Protein, Human, Recombinant (His & Avi), Biotinylated
NECL5,Necl-5,TAGE4,HVED,CD155,PVS,poliovirus re... |
Human | HEK293 Cells |
CD155/PVR Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 38.3 kDa and the accession number is P15151.2. | |||
TMPY-06133 |
CD155/PVR Protein, Human, Recombinant (hFc & Avi), Biotinylated
TAGE4,CD155,NECL5,poliovirus receptor,HVED... |
Human | HEK293 Cells |
CD155/PVR Protein, Human, Recombinant (hFc & Avi), Biotinylated is expressed in HEK293 mammalian cells with hFc and Avi tag. The predicted molecular weight is 63.6 kDa and the accession number is P15151-1. | |||
TMPJ-01231 |
Nectin-4 Protein, Mouse, Recombinant (aa 31-349, hFc)
Ig superfamily receptor LNIR,PRR4,Nectin-4,PVRL4,LN... |
Mouse | HEK293 Cells |
Nectin-4 Protein, Mouse, Recombinant (aa 31-349, hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 75-85 KDa and the accession number is Q8R007. | |||
TMPY-00762 |
CD155/PVR Protein, Mouse, Recombinant (His)
poliovirus receptor,D7Ertd458e,mE4,Taa1,ne... |
Mouse | HEK293 Cells |
CD155/PVR Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 28 kDa and the accession number is Q8K094. | |||
TMPY-05597 |
CD155/PVR Protein, Mouse, Recombinant (hFc & Avi), Biotinylated
PVS,Taa1,Tage4,CD155,poliovirus receptor,m... |
Mouse | HEK293 Cells |
CD155/PVR Protein, Mouse, Recombinant (hFc & Avi), Biotinylated is expressed in HEK293 mammalian cells with hFc and Avi tag. The predicted molecular weight is 62.9 kDa and the accession number is Q8K094. | |||
TMPJ-01232 |
Nectin-4 Protein, Mouse, Recombinant (aa 31-349, His)
PRR4,Nectin-4,Poliovirus receptor-related ... |
Mouse | HEK293 Cells |
Nectin-4 Protein, Mouse, Recombinant (aa 31-349, His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 40-50 KDa and the accession number is Q8R007. | |||
TMPJ-00312 |
Nectin-4 Protein, Human, Recombinant (mFc)
PVRL4,LNIR,Nectin-4,Ig superfamily receptor LNIR, |
Human | HEK293 Cells |
Nectin-4 Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with C-mFc tag. The predicted molecular weight is 80-90 KDa and the accession number is Q96NY8. | |||
TMPJ-00308 |
Nectin-4 Protein, Cynomolgus, Recombinant (aa 32-349, hFc)
PRR4,Ig superfamily receptor LNIR,PVRL4,Poliovi... |
Cynomolgus | HEK293 Cells |
Nectin-4 Protein, Cynomolgus, Recombinant (aa 32-349, hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 80-90 KDa and the accession number is L0N6D9. | |||
TMPJ-00311 |
Nectin-4 Protein, Human, Recombinant (aa 32-351, hFc)
PRR4,PVRL4,LNIR,Nectin-4,Ig superfamily receptor LN... |
Human | HEK293 Cells |
Nectin-4 Protein, Human, Recombinant (aa 32-351, hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 75-90 KDa and the accession number is Q96NY8. | |||
TMPJ-00309 |
Nectin-4 Protein, Cynomolgus, Recombinant (aa 32-349, His)
LNIR,Ig superfamily receptor LNIR,PRR4,Poliovir... |
Cynomolgus | HEK293 Cells |
Nectin-4 Protein, Cynomolgus, Recombinant (aa 32-349, His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 38-50 KDa and the accession number is L0N6D9. | |||
TMPJ-00310 |
Nectin-4 Protein, Human, Recombinant (His & Avi), Biotinylated
Nectin-4,PVRL4,LNIR,PRR4,Ig superfamily receptor LN... |
Human | HEK293 Cells |
Nectin-4 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-6xHis-Avi tag. The predicted molecular weight is 40-50 KDa and the accession number is Q96NY8. | |||
TMPY-00746 |
Nectin-2 Protein, Human, Recombinant (hFc)
Nectin-2,HVEB,poliovirus receptor-related ... |
Human | HEK293 Cells |
Nectin-2 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 62.3 kDa and the accession number is Q92692-2. | |||
TMPY-06383 |
Nectin-2 Protein, Human, Recombinant (His & Avi), Biotinylated
poliovirus receptor-related 2 (herpesvirus... |
Human | HEK293 Cells |
Nectin-2 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 38.80 kDa and the accession number is Q92692-2. | |||
TMPY-06295 |
Nectin-2 Protein, Human, Recombinant (hFc & Avi), Biotinylated
Nectin-2,HVEB,PVRR2,CD112,PRR2,poliovirus recep... |
Human | HEK293 Cells |
Nectin-2 Protein, Human, Recombinant (hFc & Avi), Biotinylated is expressed in HEK293 mammalian cells with hFc and Avi tag. The predicted molecular weight is 64.08 kDa and the accession number is Q92692-2. | |||
TMPY-01150 |
Nectin-2 Protein, Mouse, Recombinant (His)
MPH,Pvs,Pvr,Cd112,AI325026,AI987993,poliovirus ... |
Mouse | HEK293 Cells |
Nectin-2 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 36 kDa and the accession number is P32507-1. | |||
TMPY-05495 |
Nectin-3 Protein, Human, Recombinant (hFc)
CDw113,FLJ90624,PVRL3,DKFZp566B0846,nectin-3,PRR3,CD113,PPR3... |
Human | HEK293 Cells |
Nectin-3 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 64.4 kDa and the accession number is Q9NQS3-1. | |||
TMPJ-00323 |
Nectin-2 Protein, Mouse, Recombinant (hFc)
Herpes Virus Entry Mediator B,PVRL2,Poliovirus ... |
Mouse | HEK293 Cells |
CD112 is a type I transmembrane glycoprotein belonging to the Immunoglobulin superfamily. It comprises one Ig-like V-type domain and two Ig-like C2-type domains in the extracellular region. The V domain is believed to mediate nectin binding to its ligands. Nectin2 is known to bind the pseudorabies virus, and herpes simplex virus2 (HSV2), involving in cell to cell spreading of these viruses. It does not bind poliovirus. As a homophilic adhesion molecule, CD112 is found concentrated in adherens ju... | |||
TMPY-05196 |
PVRL1/NECTIN1 Protein, Mouse, Recombinant (hFc)
AI835281,poliovirus receptor-related 1 (he... |
Mouse | HEK293 Cells |
PVRL1/NECTIN1 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 62.9 kDa and the accession number is Q9JKF6. | |||
TMPY-05560 |
PVRL1/NECTIN1 Protein, Mouse, Recombinant (His)
PRR1,PRR,nectin-1,HIgR,Cd111,AI835281,HveC,poliovirus |
Mouse | HEK293 Cells |
PVRL1/NECTIN1 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 37.6 kDa and the accession number is Q9JKF6. | |||
TMPY-01154 |
Nectin-3 Protein, Human, Recombinant (His)
PRR3,FLJ90624,PVRL3,poliovirus receptor-re... |
Human | HEK293 Cells |
Nectin-3 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 39.3 kDa and the accession number is Q9NQS3-1. | |||
TMPY-01571 |
PVRL1/NECTIN1 Protein, Human, Recombinant (hFc)
HV1S,ED4,poliovirus receptor-related 1 (he... |
Human | HEK293 Cells |
PVRL1/NECTIN1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 61 kDa and the accession number is Q15223-1. | |||
TMPY-01572 |
PVRL1/NECTIN1 Protein, Human, Recombinant (His)
HVEC,ED4,PRR1,PVRR1,nectin-1,HIgR,poliovirus re... |
Human | HEK293 Cells |
PVRL1/NECTIN1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 35.4 kDa and the accession number is Q15223-1. | |||
TMPK-00319 |
Nectin-3 Protein, Human, Recombinant (His & Avi), Biotinylated
PVRL3,CDw113,PPR3,CD113,FLJ90624,PVRR3,PRR3 |
Human | HEK293 Cells |
The Nectin family has at least four members (Nectin-1‑4), all of which show alternate splicing, a transmembrane (TM) region (except for Nectin-1 gamma), and three extracellular Ig-domains. Nectins are highly homologous to the human receptor for poliovirus, and as such, have been alternatively-named poliovirus receptor-related proteins. They do not, however, appear to bind poliovirus. Nectin-3 (also named PRR3, CD113, and PVRL3) is an 83 kDa, type I TM glycoprotein. | |||
TMPK-00318 |
Nectin-3 Protein, Human, Recombinant (His & Avi)
PVRR3,PRR3,CDw113,FLJ90624,PVRL3,PPR3,CD113 |
Human | HEK293 Cells |
The Nectin family has at least four members (Nectin-1‑4), all of which show alternate splicing, a transmembrane (TM) region (except for Nectin-1 gamma), and three extracellular Ig-domains. Nectins are highly homologous to the human receptor for poliovirus, and as such, have been alternatively-named poliovirus receptor-related proteins. They do not, however, appear to bind poliovirus. Nectin-3 (also named PRR3, CD113, and PVRL3) is an 83 kDa, type I TM glycoprotein. Its precursor is 549 amino aci... | |||
TMPK-00471 |
PVRIG Protein, Mouse, Recombinant (hFc & Avi), Biotinylated
MGC2463,MGC104322,LPD,C7orf15,ALS2CR18,PREL2,ALS2CR9,RMO1,PR... |
Mouse | HEK293 Cells |
Murine PVRIG interacted weakly with poliovirus receptor (PVR) but bound poliovirus receptor-like 2 (PVRL2) strongly, making the latter its principal ligand.PVRIG is an inducible checkpoint receptor and that targeting PVRIG-PVRL2 interactions results in increased CD8+ T-cell function and reduced tumor growth. PVRIG Protein, Mouse, Recombinant (hFc & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-hFc-Avi tag. The predicted molecular weight is 42.7 kDa and the accession number is ... | |||
TMPK-00470 |
PVRIG Protein, Mouse, Recombinant (hFc & Avi)
PREL-2,RMO1,MGC2463,C7orf15,MGC104322,PREL2,PVRIG,LPD,MGC138... |
Mouse | HEK293 Cells |
Murine PVRIG interacted weakly with poliovirus receptor (PVR) but bound poliovirus receptor-like 2 (PVRL2) strongly, making the latter its principal ligand.PVRIG is an inducible checkpoint receptor and that targeting PVRIG-PVRL2 interactions results in increased CD8+ T-cell function and reduced tumor growth. PVRIG Protein, Mouse, Recombinant (hFc & Avi) is expressed in HEK293 mammalian cells with C-hFc-Avi tag. The predicted molecular weight is 42.70 kDa and the accession number is A0A1B0GS01. | |||
TMPK-00260 |
CD155/PVR Protein, Human, Recombinant (His & Avi)
NECL5,PVSFLJ25946,Necl-5,CD155,Tage4,PVR,HVED,FLJ25946,necti... |
Human | HEK293 Cells |
CD155 is a cell surface adhesion molecule functioning in tumor cell migration, invasion, and metastasis, and not surprisingly, is also designated as a common tumor-associated antigen. CD155 is also recognized by NK cells to induce their cytotoxicity. CD155 is also commonly referred to as the "poliovirus receptor," or PVR. |